Scalp cooling can help to retain hair during chemotherapy, but no-one keeps all of their hair. If you expect to look exactly as you did at the start of chemotherapy, you will be disappointed. The amount of hair you could retain with scalp cooling will vary for a number of reasons, and everyone should anticipate a level of shedding during treatment, even those with the highest levels of hair retention. Everyone's experience varies from person to person, however the biggest influence on hair retention is the type of chemotherapy drug you receive.